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(42) Bae, J.+, Kim, J.+, Choi, J., Lee, H. & Koh, M.*, “Split Proteins and Reassembly Modules for Biological Applications” ChemBioChem (2024), doi: 10.1002/cbic.202400123.

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(41) Lee, H.+, Kim, J.+ & Koh, M.*, “Medium-Sized Ring Expansion Strategies: Enhancing Small-Molecule Library Development” Molecules 29 (7), 1562 (2024).

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(40) Kwon, Y. S., Cho, Y. E., Kim, Y., Koh, M.* & Hwang, S*, “Dimethyloxalylglycine Suppresses SREBP1c and Lipogenic Gene Expressions in Hepatocytes Independently of HIF1A” Curr. Issues Mol. Biol. 46 (3), 2386-2397 (2024)

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(39) Tran, C. S., Yoon, M., Le, L. D., Kim, S., Kim, H., Kim, J., Nguyen, L. H., Koh, M.* & Yun, H. Y.*, “Rapid access to cis-1,3-dialkylindanes: asymmetric formal syntheses of epi-Mutisianthol and epi-Jungianol” Synthesis-Stuttgart 56, A-F (2024), doi: 10.1055/a-2249-2326.​

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(38) Baek, S. Y., Lee, J., Kim, T., Lee, H., Choi, H. S., Park, H., Koh, M., Kim, E., Jung, M. E., Iliopoulos, D., Lee, J. Y., Kim, J.* & Lee, S.*, “Development of a novel histone deacetylase inhibitor unveils the role of HDAC11 in alleviating depression by inhibition of microglial activation” Biomed., Pharmacother. 166, 115312 (2023).

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(37) Choi, J., Ahn, J., Bae, J. & Koh, M.*, “Recent synthetic biology approaches for temperature- and light-controlled gene expression in bacterial hosts” Molecules 27 (20), 6798 (2022).

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(36) Lee, S.+, Kim, J.+ & Koh, M.*, “Recent advances in fluorescence imaging by genetically encoded non-canonical amino acids” J. Mol. Biol. 434 (8), 167248 (2022) (+ equal contribution).

 

(35) Koh, M., Ahmad, I., Ko, Y., Zhang, Y., Martinez, T. F., Diedrich, J. K., Chu, Q., Moresco, J. J., Erb, M. A., Saghatelian, A.*, Schultz, P. G.* & Bollong, M. J.*, “A short ORF-encoded transcriptional regulator” Proc. Natl. Acad. Sci. U. S. A. 118 (4), e2021943118 (2021).

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(34) Holloran, N., Collins, D., Rathnayake, U., Zhang, B., Koh, M., Kang, C. & Garner, P.*, “Site-specific synthesis of cysteine-bridged glycoproteins via expressed protein glycoligation” Bioconjug. Chem. 31 (10), 2362-2366 (2020).

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(33) Zambaldo, C.+, Koh, M.+, Nasertorabi, F.+, Han, G. W., Chatterjee, A.*, Stevens, R. C.* & Schultz, P. G.*, “An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli” Bioorg. Med. Chem. 28 (20), 115662 (2020). (+ equal contribution)

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(32) Zambaldo, C.*, Vinogradova, E. V.*, Qi, X., Iaconelli, J., Suciu, R. M., Koh, M., Senkane, K., Chadwick, S. R., Sanchez, B. B., Chen, J. S., Chatterjee, A. K., Liu, P., Schultz, P. G., Cravatt, B. F. & Bollong, M. J.*, “2-Sulfonyl pyridines as tunable, cysteine-reactive electrophiles” J. Am. Chem. Soc. 142 (19), 8972-8979 (2020).

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(31) Shao, S., Koh, M. & Schultz, P. G.*, “Expanding the genetic code of the human hematopoietic system” Proc. Natl. Acad. Sci. U. S. A. 117 (16), 8845-8849 (2020).

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(30) Koh, M.+, Yao, A.+, Gleason, P. R., Mills, J. H. & Schultz, P. G.*, “A general strategy for engineering noncanonical amino acid dependent bacterial growth” J. Am. Chem. Soc. 141 (41), 16213-16216 (2019). (+ equal contribution)

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(29) Koh, M.+, Cho, H.-Y.+, Yu, C., Choi, S., Lee, K.-B.* & Schultz, P. G.*, “Site-specific incorporation of a dithiolane containing amino acid into proteins”, Bioconjug. Chem. 30 (8), 2102-2105 (2019). (+ equal contribution)

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(28) Yao, A., Reed, S. A., Koh, M., Yu, C., Luo, X., Mehta, A. P. & Schultz, P. G.*, “Progress toward a reduced phage genetic code”, Bioorg. Med. Chem. 26 (19), 5247-5252 (2018).

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(27) Xuan, W., Collins, D., Koh, M., Shao, S., Yao, A., Xiao, H., Garner, P.* & Schultz, P. G.*, “Site-specific incorporation of a thioester containing amino acid into proteins”, ACS Chem. Biol. 13 (3), 578-581 (2018).

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(26) Jang, J. Y., Koh, M., Bae, H., An, D. R., Im, H. N., Kim, H.S., Yoon, J. Y., Yoon, H. J., Han, B. W., Park, S. B. & Suh, S. W.*, “Structural basis for differential activities of enantiomeric PPARγ agonists: Binding of S35 to the alternate site”, Biochim. Biophys. Acta – Proteins and Proteomics 1865 (6), 674-681 (2017).

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(25) Koh, M., Nasertorabi, F., Han, G. W., Stevens, R. C.* & Schultz, P. G.*, “Generation of an orthogonal protein-protein interface with a noncanonical amino acid”, J. Am. Chem. Soc. 139 (16), 5728-5731 (2017).

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(24) Song, G. J., Nam, Y., Jo, M., Jung, M., Koo, J. Y., Cho, W., Koh, M., Park, S. B.* & Suk, K.*, “A novel small-molecule agonist of PPAR-γ potentiates an anti-inflammatory M2 glial phenotype”, Neuropharmacology 109, 159-169 (2016).

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(23) Park, J., Koh, M., Koo, J. Y., Lee, S. & Park, S. B.*, “Investigation of specific binding proteins to photoaffinity linkers for efficient deconvolution of target protein”, ACS Chem. Biol. 11 (1), 44-52 (2016).

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(22) Choi, S. S., Kim, E. S., Koh, M., Lee, S. J., Lim, D. H., Yang, Y. R., Jang, H. J., Seo, K. A., Min, S. H., Lee, I. H., Park, S. B., Suh, P. G. & Choi, J. H.*, “A novel non-agonist peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand UHC1 blocks PPAR gamma phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity”, J. Biol. Chem. 289 (38), 26618-26629 (2014).

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(21) Koh, M., Park, J., Koo, J. Y., Lim, D., Cha, M. Y., Jo, A., Choi, J. H. & Park, S. B.* “Phenotypic screening to identify small-molecule enhancers for glucose uptake: target identification and rational optimization of their efficacy”, Angew. Chem. Int. Ed. 53 (20), 5102-5106 (2014).

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(20) Kim, D. K., Jeong, J. H., Lee, J. M., Kim, K. S., Park, S. H., Kim, Y. D., Koh, M., Shin, M., Jung. Y. S., Kim, H. S., Lee, T. H., Oh, B. C., Kim, J. I., Park, H. T., Jeong, W. I., Lee, C. H., Park, S. B., Min, J. J., Jung, S. I., Choi, S. Y., Choy, H. E.* & Choi, H. S.* “Inverse agonist of ERRgamma controls Salmonella typhimurium infection by modulating host iron homeostasis”, Nat. Med. 20, 419-424 (2014).

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(19) Koo, J. Y., Oh, S., Cho, S. R., Koh, M., Oh, W. K., Choi, H. S.* & Park, S. B.* “Total synthesis of eryvarin H and its derivatives and their biological activity as ERRgamma inverse agonist”, Org. Biomol. Chem. 11, 5782-5786 (2013).

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(18) Kim, D. K., Gang, G. T., Ryu, D., Koh, M., Kim, Y. N., Kim, S. S., Park, J., Kim, Y. H., Sim, T., Lee, I. K., Choi, C. S., Park, S. B.*, Lee, C. H.*, Koo, S. H.* & Choi, H. S.* “Inverse agonist of nuclear receptor ERRgamma mediates antidiabetic effect through inhibition of hepatic gluconeogenesis”, Diabetes 62, 3093-3102 (2013).

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(17) Kim, D. K., Kim, Y. H., Jang, H. H., Park, J., Kim, J. R., Koh, M., Jeong, W. I., Koo, S. H., Park, T. S., Yun, C. H., Park, S. B., Chiang, J. Y., Lee, C. H.* & Choi, H. S.* “Estrogen-related receptor gamma controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol”, Gut 62, 1044-1054 (2013).

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(16) Park, J.+, Koh, M.+, & Park, S.B.* “From noncovalent to covalent bonds: a paradigm shift in target protein identification”, Mol. Biosyst. 9, 544-550 (2013). (+ equal contribution)

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(15) Kim, D. K., Ryu, D., Koh, M., Lee, M. W., Lim, D., Kim, M. J., Kim, Y. H., Cho, W. J., Lee, C. H., Park, S. B.*, Koo, S. H.* & Choi, H. S.* “Orphan nuclear receptor estrogen-related receptor gamma (ERRgamma) is key regulator of hepatic gluconeogenesis”, J. Biol. Chem. 287, 21628-21639 (2012).

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(14) Zhu, M., Lim, B. J., Koh, M. & Park, S. B.* “Construction of polyheterocyclic benzopyran library with diverse core skeletons through diversity-oriented synthesis pathway: part II”, ACS Comb. Sci. 14, 124-134 (2012).

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(13) Kim, D. K., Kim, J. R., Koh, M., Kim, Y. D., Lee, J. M., Chanda, D., Park, S. B., Min, J. J., Lee, C. H., Park, T. S. & Choi, H. S.* “Estrogen-related receptor gamma (ERRgamma) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling”, J. Biol. Chem. 286, 38035-38042 (2011).

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(12) Koh, M., Park, J., An, H. & Park, S. B.* “Ratiometric analysis of zidovudine (ZDV) incorporation by reverse transcriptases or polymerases via bio-orthogonal click chemistry”, Chem. Commun. (Camb.) 47, 7614-7616 (2011).

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(11) Kim, E., Koh, M., Lim, B. J. & Park, S. B.* “Emission wavelength prediction of a full-color-tunable fluorescent core skeleton, 9-aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one”, J. Am. Chem. Soc. 133, 6642-6649 (2011).

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(10) Srivastava, A. K., Koh, M. & Park, S. B.* “A synthetic route to highly substituted 1,2,3,4-tetrahydroisoquinolines via Yb(OTf)3 -catalyzed diastereoselective ring opening of bridged oxazolidines: asymmetric synthesis of 2-azapodophyllotoxin”, Chem. Eur. J. 17, 4905-4913 (2011).

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(9) Koh, M. & Park, S. B.* “Computer-aided design and synthesis of tetra-aryl-substituted alkenes and their bioevaluation as a selective modulator of estrogen-related receptor gamma”, Mol. Divers. 15, 69-81 (2011).

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(8) Kim, Y., Koh, M., Kim, D. K., Choi, H. S. & Park, S. B.* “Efficient discovery of selective small molecule agonists of estrogen-related receptor gamma using combinatorial approach”, J. Comb. Chem. 11, 928-937 (2009).

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(7) Kim, S. Y., Park, J., Koh, M., Park, S. B.* & Hong, J. I.* “Fluorescent probe for detection of fluoride in water and bioimaging in A549 human lung carcinoma cells”, Chem. Commun. (Camb.), 4735-4737 (2009).

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(6) Park, S. O., Kim, J., Koh, M. & Park, S. B.* “Efficient parallel synthesis of privileged benzopyranylpyrazoles via regioselective condensation of beta-keto aldehydes with hydrazines”, J. Comb. Chem. 11, 315-326 (2009).

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(5) Sagar, R., Park, J., Koh, M. & Park, S. B.* “Diastereoselective synthesis of polycyclic acetal-fused pyrano[3,2-c]pyran-5(2H)-one derivatives”, J. Org. Chem. 74, 2171-2174 (2009).

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(4) Kim, B., Lee, M., Kim, M. J., Lee, H., Kim, S., Kim, D.*, Koh, M., Park, S. B. & Shin, K. J. “Biomimetic asymmetric total synthesis of (-)-laurefucin via an organoselenium-mediated intramolecular hydroxyetherification”, J. Am. Chem. Soc. 130, 16807-16811 (2008).

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(3) Kim, E., Koh, M., Ryu, J. & Park, S. B.* “Combinatorial discovery of full-color-tunable emissive fluorescent probes using a single core skeleton, 1,2-dihydropyrrolo[3,4-beta]indolizin-3-one”, J. Am. Chem. Soc. 130, 12206-12207 (2008).

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(2) An, H., Eum, S. J., Koh, M., Lee, S. K. & Park, S. B.* “Diversity-oriented synthesis of privileged benzopyranyl heterocycles from s-cis-enones”, J. Org. Chem. 73, 1752-1761 (2008).

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(1) Lee, H. Y., Kwon, J. T., Koh, M., Cho, M. H.* & Park, S. B.* “Enhanced efficacy of 7-hydroxy-3-methoxycadalene via glycosylation in in vivo xenograft study”, Bioorg. Med. Chem. Lett. 17, 6335-6339 (2007).