최신 연구 성과
대표 논문
1. Bae, J.+, Kim, S.+, Choi, J., Kim, G., Jang, Y. & Koh, M.*, “Fluoride-Triggered Protein Activation via a Genetically Encoded Tyrosine Analogue”
J. Am. Chem. Soc., 147 (49), 45015–45024 (2025).
2. Ahn, J.+, Kim, T.+, Bae, J.+, Jung, J.+, Lee, J., Lee, H., Mun, J., Kim, S., Park, J., Kim, J.*, & Koh, M.*, “Reversible Protein Labeling via Genetically Encoded Dithiolane-Containing Amino Acid and Organoarsenic Probes” Bioconjug. Chem., 36 (5), 1034–1039 (2025).
3. Choi, J., Ahn, J., Bae, J., Yoon, M., Yun, H. & Koh, M.*, “Designing a Novel Temperature- and Noncanonical Amino Acid-Controlled Biological Logic Gate in Escherichia coli” ACS Synth. Biol., 13 (8), 2587–2599 (2024).
4. Koh, M., Ahmad, I., Ko, Y., Zhang, Y., Martinez, T. F., Diedrich, J. K., Chu, Q., Moresco, J. J., Erb, M. A., Saghatelian, A., Schultz, P. G. & Bollong, M. J., “A short ORF-encoded transcriptional regulator” Proc. Natl. Acad. Sci. U. S. A. 118 (4), e2021943118 (2021)
5. Koh, M.+, Yao, A.+, Gleason, P. R., Mills, J. H. & Schultz, P. G., "A general strategy for engineering noncanonical amino acid dependent bacterial growth" J. Am. Chem. Soc. 141 (41), 16213–16216 (2019).
6. Koh, M.+, Cho, H.-Y.+, Yu, C., Choi, S., Lee, K.-B. & Schultz, P. G., "Site-specific incorporation of a dithiolane containing amino acid into proteins", Bioconjug. Chem. 30 (8), 2102–2105 (2019).
7. Koh, M., Nasertorabi, F., Han, G. W., Stevens, R. C. & Schultz, P. G., "Generation of an orthogonal protein-protein interface with a noncanonical amino acid", J. Am. Chem. Soc. 139 (16), 5728–5731 (2017).
8. Koh, M., Park, J., Koo, J. Y., Lim, D., Cha, M. Y., Jo, A., Choi, J. H. & Park, S. B. "Phenotypic screening to identify small-molecule enhancers for glucose uptake: target identification and rational optimization of their efficacy", Angew. Chem. Int. Ed. 53 (20), 5102–5106 (2014).
9. Koh, M., Park, J., An, H. & Park, S. B. "Ratiometric analysis of zidovudine (ZDV) incorporation by reverse transcriptases or polymerases via bio-orthogonal click chemistry", Chem. Commun. (Camb.) 47, 7614–7616 (2011).